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Picosecond laser is a new type of laser technology that has attracted much attention in the field of medical cosmetology in recent years. One of its main uses is for the removal of skin pigmentation, blemishes, tattoos and eyebrow tattoos. Compared with traditional laser technology, picosecond laser pulse time is shorter and can break pigment particles more accurately without damaging surrounding tissue. Therefore, it also shows potential application in the treatment of pigmented skin diseases such as melanoma and nevus of Ohta.